
In the Season 2 finale — Shore’s directorial debut — a disgruntled former patient shoots House, and as the doc recovers, he struggles to separate hallucination from reality. In this installment, future Pretty Little Liars star Sasha Pieterse plays a young girl with terminal cancer who undergoes therapeutic hypothermia so the docs can find a blood clot. House gets parole at his hearing, but he still has to survive 5 more days in a prison filled with violent criminals. One one level, giving Wilson terminal cancer is about the cruelest ending Shore could have written both for his hero and his fans, and coming after so much relentless suffering for House it might have felt like overkill.
Lucky Thirteen

This is one of the first episodes to flesh out Wilson as a complex, flawed character in his own right, and by extension one of the first that allows Laurie and Robert Sean Leonard to really spar – always a recipe for gold. Following one long night at a glitzy hospital fundraiser, this is one of House's most flat-out fun episodes, not least because it's an excuse to get the aesthetically pleasing cast out of their lab coats and into formal wear. Quite aside from the fact that she's played by 24 icon Sarah Clarke, this episode's seemingly unflappable and high-powered Carly stands out as one of the most memorable patients-of-the-week.
Chase
A man who developed an unexplainable musical ability after an accident faces a terrible choice in "Half-Wit." Admitted with a muscle disorder, House struggles with a diagnosis, and his first attempt at treatment makes the problem worse. But when the real problem is revealed, and House figures out a treatment that will save the patient's life, he realizes it may cost the man everything he loves about life. The situation provides House an opportunity to open up about his own life, helping the woman with her dilemma, and doing some of his own healing at the same time. On the other side of the hospital, Cameron attempts to work with a homeless man who has been diagnosed with terminal cancer and is refusing treatment. In the realm of medical dramas, there are few shows as captivating and exceptional as House.
Tell Your Friends
Thrown off by the girl's mature attitude that he finds conspicuous, House then suspects that there may be something wrong with her brain. James Earl Jones — Darth Vader himself — guest stars in "The Tyrant" as a vicious African dictator named Dibala. When he's admitted to the hospital, the staff becomes uncomfortable treating him, let alone even being around him, as his past has seen him engage in ethnic cleansing and potential mass murder. As a fellow patient — a refugee from the same region — attempts to persuade doctors not to treat him, some feel it's their ethical duty. The issue becomes more complicated when Dibala openly admits to what he'll do if he survives his illness, making everyone uneasy.
House's Best Season Broke The Show's Formula (& Was Much Better For It) - Screen Rant
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One Day, One Room
Treating a drug addict patient results in House examining his life, his future and confronting his own personal demons. But as he begins to recover, and his memories start to come back to him, he is convinced that someone involved in the incident was in the middle of a medical crisis before the crash and needs his help. While House feels out-of-place in a ward of mentally ill patients, it soon becomes clear that he needs just as much help as anyone there.
Dying Changes Everything
Back on the flight, House thinks he's figured things out and must perform surgery on the first passenger who showed symptoms, but the plane's unsteadiness makes the procedure a daunting one. House is even more perplexed when his patient seemingly gets better before the operation, ultimately leading him to the real answer. She led a different life style before her marriage, House insists she hasn't changed. House and his team face a lot of moral dilemmas when a patient wants them to help him end his life. While a little girl's life and limbs are in jeopardy, Tritter becomes more manipulative and House suffers withdrawal. When all of House's efforts to rid himself of Amber fail, he turns to someone unexpected for assistance.
With compelling characters, profound thematic depth, and unparalleled narrative design, the best episodes of House continue to resonate with audiences and echo through the annals of television history. House treats a patient who is convinced she's dying because of a death predicting cat. Meanwhile Taub catches up with an old High School classmate and contemplates leaving the team. This episode — which earned two Emmy nominations and a win for director Greg Yaitanes — follows House as he eventually identifies former coworker Amber (Anne Dudek), who was dating Wilson (Robert Sean Leonard), as the bus crash victim dying in a vision of his. With no familiar supporting characters (save a brief appearance from Wilson) the focus is solely on Laurie's spectacular performance, and though the episode veers slightly into sentimentality, it's no bad thing after the unremittingly bleak fifth season. From a soapy premise – a long-term coma patient is woken up for just one day in order to save his dying son – comes the third season's most subtle and intense hour.
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But when he is frustrated by the care doled out by the attending Dr. Nolan, House takes it upon himself to diagnose his fellow patients in the ward, while doing everything he can to get himself out. But when Cuddy won't give House permission to perform an autopsy on the dead cop, he'll go to great lengths to get the examination he needs to save the day. While working in the clinic, House also helps diagnose a preschooler whose mother thinks her daughter's seizures may be the result of epilepsy. "Under My Skin" sees House struggling with insomnia and finally realizing what may be causing it. In the process, the two doctors grow closer, culminating in a passionate physical encounter that threatens to throw their personal and professional lives upside down. A second plot involves a seemingly disturbed patient who comes into the clinic, having tried to mutilate his own genitals.
Wilson winds up getting into trouble while trying to talk House into doing the right thing, as police discover an old search warrant for an incident in Louisiana. Simply click on the interactive rating graph to explore the best and worst of House's 177 episodes. A famous jazz trumpeter, diagnosed with ALS, signs a DNR form, but because House believes the diagnosis wrong, he breaks the law by resuscitating him. The team takes care of a student with inexplicable electrical shocks, and House's parents visit.
A structurally ingenious yarn that dovetails its initially playful format into an emotionally revealing backstory, 'Three Stories' is arguably the best single episode of House ever. Laurie is masterfully subtle at depicting both House's withdrawal and his denial, and the scene in which he breaks his own hand is a compelling glimpse at the self-destructive spiral yet to come. Below, Digital Spy looks back on the very best of Laurie's tormented diagnostician, naming our favourite 13 episodes in chronological order. Cuddy, House and members of the team join forces with a search-and-rescue team to provide much-needed medical attention at the scene of an emergency.
Meanwhile at the hospital, the staff treat a man suffering from a mysterious respiratory problem. When they go to his home for more information, they make a surprising discovery about him. House's preoccupation with Wilson leaves his team without direction and endangers the patient, a female whose exhaustive work schedule and demanding boss may have caused her condition. The search for the cause of a supermodel's symptoms causes intense feelings among the team, as new facts are revealed. House takes on a case where the patient has unexplained blackouts, and his daughter may hold the key to the diagnosis.
The Season 1 episode "Three Stories" features guest star Sela Ward as Stacy, Dr. House's ex, who comes back into his life when she needs him to help diagnose her new husband. Bumping into his Stacy while on his way to a giving a lecture, House dismisses the idea of helping her husband — clearly out of spite. While speaking to a small group of students later, House lectures them on the cases of three separate patients, shown via flashbacks. "Autopsy" sees a young girl named Andie, who's been diagnosed with terminal cancer, bravely dealing with her chemo treatment when she begins to suffer from hallucinations. When an examination shows her cancer is actually in remission, House realizes the new symptoms must be unrelated and gets to work on a new diagnosis.
Thirteen comes to Chase with a confidential case in "After Hours," when one of her former cellmates in prison shows up with a vicious stab wound. On the run from police, Thirteen's ex-con friend Darrien (guest star Amy Landecker) needs help from the doctors off the books. But when her problems get worse and she loses feeling in her arm, Chase demands they admit her.
House claims there's a victim on the bus who is dying, but not from the bus accident. He stops at nothing to figure out who the patient is and what is ailing him/her. As House listens to the shooter blame all his problems on him, he's forced to confront his own weaknesses as his mental state deteriorates.
As the episodes' titles imply, they're a perfect one-two punch, with the first boggling your mind just in time for the second to break your heart. While helping treat a young heroin addict named Oliver, House begins to look back and face up to his many transgressions. As he re-examines his life, House hallucinates the many people that have come and gone throughout his life, including long dead colleagues and friends. Jeffrey Wright guest stars in Season 8 episode "Nobody's Fault" as Dr. Walter Cofield, a brilliant neurosurgeon and former mentor to House. Now the Chief of Neurology, Dr. Cofield puts House under review after a case involving a violent, mentally disturbed man nearly leads to the death of a hospital staff member.
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